Peroxisomal membrane permeability and solute transfer
نویسندگان
چکیده
منابع مشابه
Peroxisomal membrane permeability and solute transfer.
The review is dedicated to recent progress in the study of peroxisomal membrane permeability to solutes which has been a matter of debate for more than 40 years. Apparently, the mammalian peroxisomal membrane is freely permeable to small solute molecules owing to the presence of pore-forming channels. However, the membrane forms a permeability barrier for 'bulky' solutes including cofactors (NA...
متن کاملPermeability of the peroxisomal membrane: lessons from the glyoxylate cycle
Glyoxylate serves as intermediate in various metabolic pathways, although high concentrations of this metabolite are toxic to the cell. In many organisms glyoxylate is fed into the glyoxylate cycle. Enzymes participating in this metabolism are located on both sides of the peroxisomal membrane. The permeability of this membrane for small metabolites paves the way for exchange of intermediates be...
متن کاملThe VDAC2–BAK axis regulates peroxisomal membrane permeability
Peroxisomal biogenesis disorders (PBDs) are fatal genetic diseases consisting of 14 complementation groups (CGs). We previously isolated a peroxisome-deficient Chinese hamster ovary cell mutant, ZP114, which belongs to none of these CGs. Using a functional screening strategy, VDAC2 was identified as rescuing the peroxisomal deficiency of ZP114 where VDAC2 expression was not detected. Interestin...
متن کاملEffect of Various Solute Concentrations on the Membrane Permeability of Rbcs in Human Blood
The development in the field of medicine has been immense in the past few decades. As the rate of diseases in humans as well as accidents is increasing, there is a constant need of the blood for the transfusion. The number of blood donors is limited, so the blood needs to be stored. A great care is needed to preserve the blood components specially RBCs. The integrity and physiology of the RBCs ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
سال: 2006
ISSN: 0167-4889
DOI: 10.1016/j.bbamcr.2006.08.044